Coronavirus genomes carry the signatures of their habitats.

Coronaviruses such as SARS-CoV-2 regularly infect host tissues that express antiviral proteins (AVPs) in abundance.Understanding how they evolve to adapt or evade host immune responses is important in the effort to control the spread of infection.Two AVPs that may shape viral genomes are the zinc finger antiviral protein (ZAP) and the apolipoprotei

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The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health

SLC7A5, known as LAT1, belongs to the APC superfamily and forms a heterodimeric amino acid transporter interacting with the glycoprotein CD98 (SLC3A2) through a conserved disulfide.The complex is responsible for uptake of essential amino acids in crucial body districts such as placenta and blood brain barrier.LAT1/CD98 heterodimer has been studied

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